Skip to main content
Figure 6 | Respiratory Research

Figure 6

From: Loss of a single N-linked glycan from the hemagglutinin of influenza virus is associated with resistance to collectins and increased virulence in mice

Figure 6

S and Mo variants of Beij/89 are lethal for RAG1 -/- mice but L variants are not. Groups of 5 mice infected with 105 PFU of Beij/89 viruses via the intranasal route were examined daily for weight loss and signs of disease. (A) Weight loss and (B) survival curves are shown for mice inoculated with L, S or Mo viruses. Mice were weighed daily and results expressed as the mean percent weight change of each group (± SEM), compared to original body weight. Animals that had lost ≥20% of their original body weight and/or presented with evidence of pneumonia were euthanized.

Back to article page