Figure 3

Effects of RGDS on LPS-induced increases in total protein levels in BAL fluid. Where indicated, mice were administered i.p. RGDS (1, 2.5 or 5 mg/kg) or RGES (5 mg/kg) once 1 h before LPS and sacrificed 4 h post-LPS (A). Mice were also administered these peptides (5 mg/kg, i.p.) once 1 h before or 2 h after LPS and were sacrificed 24 h post-LPS (B). Values represent means ± SEM of 5 mice per group. *Significantly different from saline treated controls, p < 0.05; ⁺significantly different from animals treated with LPS only, p < 0.05.