Figure 3From: Particles induce apical plasma membrane enlargement in epithelial lung cell line depending on particle surface area dose Surface area of the apical plasma membrane of A549 cells at different particle concentrations. * = p < 0.01 vs. negative control (NC). The mass of 3 × 107 1 μm particles and the surface area of 6 × 108 1 μm particles are approximately equal to the mass and surface area of 4.5 × 1011 0.05 μm particles, respectively. Increases in the surface area of the APM were observed at the same particle surface area concentration exposed to the cells. n = 5.Back to article page