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Figure 7 | Respiratory Research

Figure 7

From: Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

Figure 7

mRNA expression in the right ventricle, relative to the expression in the left ventricle and interventricular septum, determined with RT-PCR, of atrial natriuretic peptide (ANP; panel A), brain natriuretic peptide (BNP; panel B), c-type natriuretic peptide (CNP; panel C), natriuretic peptide receptor (NPR) -A (panel D), NPR-B (panel E) and NPR-C (panel F) in room air-exposed controls (RA, white bars), age-matched O 2 -exposed controls (O 2 , black bars) and sildenafil-treated rat pups (100 mg/kg/day [Sil 100 ], gray bars) under hyperoxia on day 10. Data are expressed as mean ± SEM of 10 rat pups. *p < 0.05, **p < 0.01 and ***p < 0.001 versus age-matched O2-exposed controls.Δ p < 0.05, ΔΔ p < 0.01 and ΔΔΔ p < 0.001 versus room air-exposed controls.

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