Figure 7From: Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury mRNA expression in the right ventricle, relative to the expression in the left ventricle and interventricular septum, determined with RT-PCR, of atrial natriuretic peptide (ANP; panel A), brain natriuretic peptide (BNP; panel B), c-type natriuretic peptide (CNP; panel C), natriuretic peptide receptor (NPR) -A (panel D), NPR-B (panel E) and NPR-C (panel F) in room air-exposed controls (RA, white bars), age-matched O 2 -exposed controls (O 2 , black bars) and sildenafil-treated rat pups (100 mg/kg/day [Sil 100 ], gray bars) under hyperoxia on day 10. Data are expressed as mean ± SEM of 10 rat pups. *p < 0.05, **p < 0.01 and ***p < 0.001 versus age-matched O2-exposed controls.Δ p < 0.05, ΔΔ p < 0.01 and ΔΔΔ p < 0.001 versus room air-exposed controls.Back to article page