From: Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
Treatment-stratified analysis | |||||
---|---|---|---|---|---|
SNP | Genic location | MAF | All subjects (n = 654) | Budesonide (n = 214) | Placebo or Nedocramil (n = 440) |
rs6671164 | 5' genomic | 0.223 | 0.002 | - | 0.004 |
rs4448553 | 5' genomic | 0.223 | 0.02 | - | 0.01 |
rs1990150 | Intron 1 | 0.148 | 0.02 | - | 0.04 |
rs2240447 | Exon 2 | 0.224 | - | - | - |
rs2486014 | Intron 2 | 0.097 | 0.04 | - | - |
rs2301993 | Intron 12 | 0.222 | 0.002 | - | 0.001 |
rs2301992 | Intron 13 | 0.049 | 0.02 | - | 0.03 |
rs1636879 | Intron 14 | 0.102 | 0.02 | - | 0.04 |
rs7412307 | 3' genomic | 0.184 | 0.02 | - | 0.04 |
rs2428953 | 3' genomic | 0.11 | 0.002 | - | 0.005 |