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Figure 4 | Respiratory Research

Figure 4

From: Gene promoter methylation assayed in exhaled breath, with differences in smokers and lung cancer patients

Figure 4

Methylation maps of DAPK, RASSF1A, PAX5β promoter from Exhaled Breath Condensate. The promoter methylation status of DAPK, RASSF1A, PAX5β, was mapped using tBGS. Overall, both the methylation density and patterns of DAPK, RASSF1A or PAX5β promoters differed quite dramatically between individuals within any given smoking or clinical stratum. Methylation density is given at right, for individuals and group means. [NSCCa: non-small cell lung cancer: SCCa: Small cell lung cancer; SqCCa: squamous cell lung cancer; AdCa: Adenocarcinoma; AdBaCa: Adenocarcinoma with bronchalveolar features]. Data on smoking status (never, former and current), pack year, quit years and for tumors, histology and stages I, II, III, IV are given at left.

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