Figure 3From: Truncating and missense BMPR2 mutations differentially affect the severity of heritable pulmonary arterial hypertension Age at diagnosis of PAH: comparison of noncarriers, patients carrying a truncating BMPR2 mutation, and patients carrying a missense BMPR2 mutation. Age at diagnosis is no different between noncarriers and patients carrying a truncating BMPR2 mutation. There is a significant difference in age at diagnosis between noncarriers and patients carrying a missense BMPR2 mutation (*, P = 0.002). Values represent mean age at diagnosis; error bars represent 95% confidence intervals.Back to article page