NMD status of BMPR2 mutation | 'NMD active' (Truncating) (n = 55) | 'NMD absent' (Missense) (n = 41) | P value* |
---|---|---|---|
Age at Diagnosis, yrs | 39.9 (36.3-43.5) | 30.6 (25.9-35.3) | 0.004 |
Gender, female/male | 2.6/1 | 1.7/1 | 0.82 |
RAP, mm Hg | 11.4 (7.4-15.3) | 10.5 (8.1-13.0) | 0.74 |
Mean PAP, mm Hg | 56.5 (51.6-61.5) | 60.0 (54.9-65.2) | 0.42 |
PCWP, mm Hg | 11.1 (8.5-13.6) | 10.3 (8.4-12.2) | 0.74 |
CI, L/min/m2 | 1.8 (1.5-2.1) | 1.9 (1.8-2.1) | 0.16 |
PVR, mm Hg/L/min | 18.4 (11.4-25.3) | 17.9 (12.7-23.1) | 0.78 |
SvO2, % | 58.6 (51.2-65.3) | 57.3 (52.8-61.7) | 0.19 |