Figure 3
From: The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure
Representative transmission electron microscope pictures of the surfactant ultrastructure. A) and B) untreated control surfactant. C) and D) porcine surfactant after addition of 100 μg/ml TiO2 nanosized particles. Red circles show small particle aggregates. E) Control surfactant after 8 hours rotation at 0.43 Hz and 37°C. F) Surfactant after 8 hours rotation at 0.43 Hz and 37°C in the presence of 100 μg/ml TiO2 nanosized particles. Black arrows show large particle aggregates; lbl - lamellar body like forms; ulv - unilamellar vesicles.