Collagen V-induced nasal tolerance downregulates pulmonary collagen mRNA gene and TGF-beta expression in experimental systemic sclerosis

Table 2 The TGF-beta expression in vessels and septal interstitium from lungs of control, immunized and type V-induced nasal tolerance rabbits groups

	CONTROL	IMMUNIZED	TOLERATED	P
VESSEL
Endothelium cells	6.7 ± 3.85	43.5 ± 5.7	10.77 ± 4.3	*p < 0.0001
Smooth muscle cells	11.04 ± 1.0	53.68 ± 4.06	9.93 ± 3.77	*p < 0.0001
SEPTAL INTERSTITIUM
Epithelial cells	5.04 ± 2.46	13.65 ± 1.39	6.03 ± 1.47	*p < 0.0001
Interstitial Fibroblasts	8.55 ± 1.96	20.13 ± 1.60	11.55 ± 1.88	*p < 0.0001

* p = immunized vs. tolerated; ANOVA with Bonferroni test was employed to statistical analysis.
The results are reported as cells/mm².

ISSN: 1465-993X