From: Asthma and gender impact accumulation of T cell subtypes
Culture stimulus | T cell subset | Asthma group | Accumulation, % of day 0 numbers * | p-value † | |||||
---|---|---|---|---|---|---|---|---|---|
Gender | Steroid • | Geo. Mean | Geo. Mean ± S.D. | n | Gender | Steroid | Interaction | ||
IL-2 | IL-13+ | Female | No | 622 | 326 - 1184 | 6 | 0.0016 | 0.16 | 0.22 |
Yes | 662 | 342 - 1280 | 5 | ||||||
Male | No | 116 | 73 - 184 | 2 | |||||
Yes | 285 | 155 - 525 | 5 | ||||||
IFN-γ+ | Female | No | 677 | 229 - 1994 | 6 | 0.41 | 0.28 | 0.40 | |
Yes | 170 | 69 - 420 | 4 | ||||||
Male | No | 206 | 101 - 423 | 3 | |||||
Yes | 173 | 21 - 1415 | 6 | ||||||
CD3+CD28 | IL-13+ | Female | No | 5427 | 1281-22,996 | 3 | 0.0016 | 0.044 | 0.33 |
+ IL-2 | Yes | 1352 | 571 - 3,201 | 6 | |||||
Male | No | 656 | 393 - 1,094 | 3 | |||||
Yes | 388 | 204 - 738 | 6 | ||||||
IFN-γ+ | Female | No | 3730 | 886 - 15,702 | 3 | 0.073 | 0.023 | 0.98 | |
Yes | 691 | 241 - 1,982 | 6 | ||||||
Male | No | 1035 | 396 - 2,707 | 3 | |||||
Yes | 186 | 36 - 962 | 7 |