From: Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis
Drug Class | mPAP | mRAP | PVR | Cardiac Index |
---|---|---|---|---|
Prostanoids | -4.2 (-6.2, -2.1) | -1.6 (-2.3, -0.9) | -291 (-401, -182) | 0.32 (0.12, 0.52) |
Endothelin receptor antagonists | -4.9 (-6.6, -3.2) | -1.4 (-2.9, 0.2) | -245 (-316, -174) | 0.30 (0.09, 0.51) |
Phosphodiesterase type 5 inhibitors | -4.2 (-5.7, -2.7) | -1.8 (-2.8, -0.8) | -192 (259, 126) | 0.39 (0.15, 0.63)* |