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Figure 4 | Respiratory Research

Figure 4

From: Expression and function of human hemokinin-1 in human and guinea pig airways

Figure 4

Contraction induced with single additions of 10 -6 M hHK-1 (left graph, n = 6-12) or 10 -6 M specific NK 1 receptor agonist [Sar 9 ,Met(O 2 ) 11 ] SP (right graph, n = 6) on human bronchi in the absence (control) and presence of NK 1 or NK 2 receptor antagonists SR 140333 and SR 48968 (10 -7 M). Experiments were performed in the presence of phosphoramidon (10-6 M). Values are expressed in percentage (mean ± s.e.m.) of maximal contraction obtained with ACh 3 mM. Statistical analysis was performed with one-way ANOVA followed with Bonferroni post-test. ** p < 0.01 and *** p < 0.001 versus paired control.

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