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Table 3 Characteristics of study subjects

From: Mutations that permit residual CFTR function delay acquisition of multiple respiratory pathogens in CF patients

 

'Minimal' Function

'Residual' Function

p value

Individuals

1218

163

 

Female

579 (47.5%)

81 (49.7%)

0.605 a

Caucasian

943 (95.5%)

115 (83.9%)

<0.001 b

Pancreatic Insufficient

1180 (97.8%)

46 (30.3%)

<0.001 b

Age (yrs) last visit ± SD (range), (n)

15.82 ± 8.60 (0.44-57.31) (1209)

18.59 ± 12.87 (0.54-63.94) (159)

0.133b

Maximal FEV 1 CF% since last clinic visit, (n)

0.68 ± 0.26 (1111)

0.75 ± 0.25 (145)

<0.001 b

Average number of cultures per subject per year ± SD, (n)

3.89 ± 1.92 (1201)

3.93 ± 2.27 (159)

0.530 b

  1. Definition of abbreviations: Maximal FEV1 CF%: CF specific percentile for the maximum forced expiratory volume in one second in the last year of data for the subject.
  2. a: P-value reported from chi-squared, assumes equal variance in group means.
  3. b: P-value reported from Kruskal-Wallis test due to unequal variances in group means.