Decreased Toll-like receptor 8 expression and lower TNF-alpha synthesis in infants with acute RSV infection

Respiratory Research

Table 2 Correlations of clinical data and experimental findings.

Clinical findings	% TLR8⁺ monocytes (n = 15)	TLR8 MFI in monocytes (n = 15)	% TNF-α⁺ monocytes (n = 10)	TNF-α MFI in monocytes (n = 10)
Age (months)	-0.40	-0.41	0.01	-0.27
WBC count (x10⁹/L)	0.23	0.34	-0.48	-0.09
Wheezing duration (days)	0.02	0.32	-0.23	-0.55
MOS (%)	-0.01	-0.05	0.73	0.66
Oxygen supplementation (days)	0.22	0.10	0.16	0.31
Heart rate (/min.)	-0.11	-0.45	-0.05	0.19
MRR (/min.)	-0.05	-0.59	0.37	0.26
Hospital stay (days)	-0.21	-0.16	0.18	0.55

Overall statistical correlations of clinical data from RSV infected infants and experimental findings were assessed by Spearman rank correlation test. Numbers represent Spearman rank correlation coefficients and those with significant p-values (≤ 0.05) are in bold.
WBC - white blood cells, MOS - minimal oxygen saturation measured by percutaneous oxymetry breathing ambient air, MRR - maximal respiratory rate (frequency) during hospitalization period

ISSN: 1465-993X