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Table 4 Biochemistry and Systemic Inflammatory status

From: Cardiovascular and musculskeletal co-morbidities in patients with alpha 1 antitrypsin deficiency

 

Control

n = 20

Patient

n = 19

P value

Total cholesterol (mmol/l)

5.8 (1.0)

5.7 (1.4)

0.66

HDL (mmol/l)

1.6 (0.3)

1.7(0.5)

0.44

LDL (mmol/l)

3.7 (1.0)

3.5 (1.2)

0.58

Triglycerides # (mmol/l)

1.19 (0.49)

0.98 (0.31)

0.12

Fasting Glucose (mmol/l)

5.2 (0.6)

4.9 (0.5)

0.06

Creatinine (μmol/l)

88.4 (18.1)

84.0 (12.6)

0.39

eGFR (mls/min/1.73 m 2 )

75.9 (15.6)

79.4 (12.1)

0.44

Testosterone(males)nmol/l #

15.6 (1.2)

24.6 (1.4)

0.001

IL-6 (pg/ml)#

2.18 (1.62)

3.24 (1.62)

0.016

  1. All data represented as mean (standard deviation) unless otherwise indicated,
  2. # geometric mean
  3. Abbreviations: HDL High Density Lipoprotein, LDL Low density Lipoprotein, eGFR Estimated Glomerular Filtration Rate; IL-6 Interleukin 6