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Figure 1 | Respiratory Research

Figure 1

From: Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered

Figure 1

Diaphragm force generation. Upper panel: Force-frequency relationship in the diaphragm of controls (C, open rectangles, n = 9), controlled mechanical ventilation animals treated either with saline (CMV, closed triangles, n = 9) or with 5 mg/kg methylprednisolone (MP-5, open circles, n = 7) or 30 mg/kg methylprednisolone (MP-30, closed circles, n = 6). Maximal tetanic tension in the diaphragm of C, CMV, MP5 and MP30 groups. Values are means ± SD. *p < 0.001 CMV and MP-5 vs others, #p < 0.01 CMV vs C and MP-30, ++p < 0.01 MP-5 vs MP-30, +p < 0.05 MP-5 vs MP-30.

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