Figure 5From: Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27kip1 in rats Effects of β-E2 on mRNA expression in rat lungs and cultured PASMCs. (a) Analysis of p27 and Skp-2 mRNA levels in rat lungs. (b) Analysis of p27 and Skp-2 relative mRNA levels in cultured rat PASMCs. *P < 0.01, significant difference from the hypoxia group. # P < 0.01, significant difference from the normoxia group. $ P < 0.05, significant difference from the hypoxia group. & P < 0.01, significant difference from the normoxia group. Values are expressed as mean ± SD (n = 3).Back to article page