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Table 1 Constitutive surface expression of TLR2, TLR4 and TLR9

From: Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes

Receptor

% Cells expressing TLRs

Cell Surface Expression (rMFI)

 

MN

AM

MDM

MN

AM

MDM

TLR2

57 ± 11.1

1.2 ± 0.4*

1.5 ± 1.2*

3.2 ± 0.1

0.9 ± 0.1*

1.4 ± 0.5*

TLR4

3.0 ± 0.8

1.3 ± 0.2

3.8 ± 1.4

1.5 ± 0.2

1.1 ± 0.1

1.3 ± 0.3

TLR9

39.8 ± 14.7

54.6 ± 15.5

38 ± 20

4.4 ± 1.4

218.4 ± 187.3*

3.6 ± 0.9

  1. Constitutive surface expression of TLR2, TLR4 and TLR9 on human monocytes and alveolar macrophages and monocyte-derived macrophages. TLR levels were determined on monocytes (MN, n = 8), alveolar macrophages (AM, n = 7) and monocyte-derived macrophages (MDM, n = 8) by flow cytometry. Results present mean percentages ± SE of cells expressing TLR and relative mean fluorescence index (rMFI) ± SE as a measure of the TLR expression density. (*) statistically significant differences compared to monocytes (p < 0.05).