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Table 1 Patient Demographics

From: Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

Criteria

Control Subjects

Mild to Moderate Asthmatic Subjects

Number

16

18

Sex (M/F)

6/10

7/11

Age, yr

25.2 ± 6.0

25.9 ± 9.4

Antileukotrienes

0

2

Inhaled Steriods

0

9

FEV1 % predicted

105.6 ± 11.4

90.2 ± 14.3‡

FEV1/FVC % predicted

101.5 ± 4.1

87.6 ± 9.8§

PC20 (mg/ml)

>16

1.0 (0.48-2.1)†

Squamous cells (%)

1.5 (3.8)*

2.0 (6.0)*

Lung Epithelial cells (%)

2.0 (5.3)*

2.5 (3.0)*

Eosinophils (%)

1.1 (3.0)*

2.0 (6.0)*

Neutrophils (%)

19.85 (21.1)*

6.95 (17.8)*

  1. Values are reported as means ± SD unless otherwise indicated. Definition of abbreviations: F = females, FEV1 = forced expiratory volume in 1 second, FEV1/FVC = FEV1/forced vital capacity, M = males, PC20 = provocation concentration of methacholine causing a 20% fall in FEV1. The percentage of eosinophils and neutrophils are reported for induced sputum.
  2. †Geometric mean (range)
  3. *Median (interquartile range)
  4. ‡p = 0.004, asthmatic vs. control group
  5. §p < 0.0001, asthmatic vs. control group