Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD

Respiratory Research

Table 4 Linear Regression Analysis (Quantification Langerin+ DC in small airways)

DC surface marker	R²	Predictor Variable	β	p
Langerin+ DC in Total Airway Wall	0.23	FEV₁(% pred)	-0.436	0.002
		Age	-0.088	0.441
		Gender	0.186	0.105
		Packyear	0.065	0.592
		Smoking status	0.011	0.920
		Inhaled CS	0.006	0.968
		Oral CS	0.047	0.705
Langerin+ DC in Epithelium	0.20	FEV₁(% pred)	-0.398	0.006
		Age	-0.049	0.674
		Gender	0.130	0.264
		Packyear	0.031	0.805
		Smoking status	0.090	0.427
		Inhaled CS	0.019	0.898
		Oral CS	0.046	0.715
Langerin+ DC in Lamina Propria	0.16	FEV₁(% pred)	-0.350	0.018
		Age	-0.076	0.525
		Gender	0.160	0.179
		Packyear	0.111	0.381
		Smoking status	0.078	0.503
		Inhaled CS	-0.093	0.542
		Oral CS	0.125	0.336
Langerin+ DC in Adventitia	0.40	FEV₁(% pred)	-0.434	0.001
		Age	0.045	0.673
		Gender	0.217	0.039
		Packyear	-0.028	0.799
		Smoking status	0.115	0.271
		Inhaled CS	0.187	0.176
		Oral CS	0.072	0.542

Abbreviations: DC: dendritic cell; FEV1(% pred): forced expiratory volume in one second (% predicted); CS: corticosteroids.
β:standardized coefficient. Smoking status: current versus non-current smoker
Significant p values are marked in bold.

ISSN: 1465-993X