Figure 4From: Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamstersChanges in the remodeling of pulmonary arterioles and RVSP after chymase inhibition with chymostatin. (a) Representative van Gieson's elastic staining of small pulmonary vessels (original magnification × 40). Scale bars = 100 μm. Con: control; CS: cigarette smoke exposure; Chy: treatment with 2 mg/kg chymostatin alone; CS+Chy: treatment with smoke exposure plus 2 mg/kg chymostatin. (b) MWT of pulmonary arterioles. (c) RVSP. Control: control group; CS: cigarette smoke-exposed group; Chymo: chymostatin treatment. Values are expressed as mean ± SD (n = 6). * P < 0.05, significant difference from the control group. # P < 0.05, significant difference from the smoke-exposed group.Back to article page