| Mac | Epi | Eos | Neut | Lymph |
---|
Balb/c-PBS
| 0.9 ± 0.4 | 1.8 ± 0.6 | 0 | 0.04 ± 0.02 | 0.07 ± 0.06 |
PAR2-/- PBS
| 2.0 ± 0.7 | 3.0 ± 1.2 | 0 | 0.02 ± 0.02 | 0.04 ± 0.02 |
Balb/c-frass
| 7.8 ± 0.9* | 5.2 ± 1.1 | 4.7 ± 1.3* | 5.9 ± 3.9* | 2.9 ± 0.7* |
PAR2-/- frass
| 3.8 ± 0.9** | 3.1 ± 1.2 | 1.7 ± 0.8** | 0.8 ± 0.2** | 2.3 ± 0.9* |
- Wild type (Balb/c) or PAR-2-deficient mice were given intratracheal inhalations of PBS (40 μl) or GC frass (40 μg/40 μl) on days 0, 7, and 14. On day 17, BAL fluid was harvested and differential cell counts performed. These data represent 4 mice per group and are expressed as mean ± SEM of cell number × 104. Cell counts were statistical significance between GC frass and PBS exposed mice (*p < 0.05, as determined by ANOVA). In addition, statistical differences were found between Balb/c and PAR-2-deficient mice exposed to GC frass (**p < 0.05).