Figure 4From: K+ channel openers restore verapamil-inhibited lung fluid resolution and transepithelial ion transportComparison of verapamil-inhibitable Isc levels in H441 monolayers when applied to the apical or basolateral compartments. (A-C) Representative Isc traces showing the effects of water (H2O), verapamil applied to basolateral (B) and apical (C) compartments. The total AS Isc levels associated with ENaC are designated by pairs of vertical arrows. (D) AS Isc levels before and after verapamil delivery to the basolateral side or apical compartment. Paired t-test for comparison of current levels before and after verapamil. *P < 0.05 and **P < 0.01. n = 4-17.Back to article page