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Figure 8 | Respiratory Research

Figure 8

From: K+ channel openers restore verapamil-inhibited lung fluid resolution and transepithelial ion transport

Figure 8

Compartment-dependent recovery of verapamil-inhibited Isc levels by K+channel openers in permeabilized H441 monolayers. (A) Representative Isc traces of apical Isc level in the presence of 1 mM ouabain in the basolateral membrane permeabilized monolayers. (B) Representative Isc traces of basolateral Isc level in the presence of 100 mM amiloride in the apical permeabilized H441 monolayers. (C & D) Recovered apical (C) and basolateral (D) Isc levels by K+ channel openers. One-way ANOVA for comparing normalized Isc level post K+ channel openers with total AS or OS Isc levels. *P < 0.05 and **P < 0.01. n = 3-5.

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