Adventitia | Lumen |
|---|
-0.89, P < 0.05, N = 5 | -0.87, NS, N = 4 |
-0.76, P < 0.05, N = 7 | -0.54, NS, N = 5 |
-0.86, P < 0.05, N = 6 | -0.71, NS, N = 6 |
-0.97, P < 0.001, N = 7 | -0.56, NS, N = 6 |
- Data are from eight different airway preparations that were constricted to carbachol administered either to the adventitial or luminal airway surface. Time to 50% response of airway narrowing was used as an index of the rate of airway narrowing and was plotted against airway generation. When carbachol was administered to the adventitial surface time to 50% response was negatively correlated with airway generation indicating a faster rate of narrowing at distal locations. In comparison, when carbachol was added to the luminal surface correlations were not significant. N = number of data points available for each individual airway. (Pearson's correlation analysis)
