Figure 6
IL-8 production by PCBG activated cells is not impaired in the presence of a pharmacological inhibitor of JNK-II. 1HAEo- cells were incubated with 100 ug/ml of PCBG for a period of eight hours. Prior to the addition of PCBG, the cells were preincubated for one hour with JNK Inhibitor II at the concentration indicated. IL-8 secretion was measured by ELISA in the media supernatant of the cells. Data were analyzed with one-way ANOVA and posttest Bonferroni comparison (not significantly different, p > 0.05). The data shown is representative of two independent experiments.