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Table 4 Studies which report the comparison of symptoms and quality of life

From: Statins as potential therapeutic drug for asthma?

Study

Study type

Group

Sample (Trial/Control)

Duration of treatment

Results (statin group compared with the control group)

Braganza et al., [16]

RCT

Atorvastatin(40mg/day) vs placebo

71

4 weeks

ACQ and AQLQ (p=0.005) ↑

Hothersall et al., [22]

RCT

Atorvastatin(40mg/day) vs placebo

54

8 weeks

No significant difference

Cowan et al., [25]

RCT

Simvastatin(40mg/day) vs placebo

43

4 weeks

ACQ (p=0.037) ↓

  1. ACQ= Asthma Control Questionnaire; AQLQ= Asthma Quality of Life Questionnaire.
  2. ↑ The symptoms and quality of life were improved in statin group compared with the control group, ↓ an opposite result.