Table 3 Hazard ratios for dying after admission for acute exacerbation of COPD

Age, per 5 years

1.3 (1.08-1.5)

0.003

0.99 (0.83-1.2)

0.872

0.95 (0.78-1.2)

0.643

0.98 (0.75-1.3)

0.860

Female

1.4 (0.81-2.3)

0.252

2.0 (1.1-3.6)

0.020

1.7 (0.87-3.3)

0.119

2.8 (1.2-6.8)

0.020

Peripheral edema

3.2 (1.9-5.5)

<0.0001

2.1 (1.2-3.8)

0.014

2.1 (1.0-4.2)

0.044

2.6 (1.1-6.1)

0.032

Cephalization

4.5 (2.5-8.0)

<0.0001

2.2 (1.2-4.2)

0.014

2.2 (1.0-4.8)

0.049

3.4 (1.2-9.8)

0.022

hs-cTnT, ng/L

p for trend 0.0001

p for trend 0.004

p for trend 0.008

p for trend 0.004

<14

1

1

1

1

14-40

6.3 (1.9-21)

0.003

4.3 (1.2-15)

0.024

4.5 (1.3-16)

0.021

9.4 (1.2-77)

0.036

≥40

12 (3.5-38)

<0.0001

6.5 (1.8-24)

0.005

6.4 (1.7-24)

0.007

16 (1.7-140)

0.013

NT-proBNP, tertile

p for trend <0.0001

p for trend 0.013

p for trend 0.030

p for trend 0.211

1(< 264.4 pg/mL)

1

1

1

1

2 (264.4-909 pg/mL)

4.3 (1.8-10)

0.0009

2.4 (0.95-6.0)

0.064

2.7 (1.0-7.4)

0.049

2.1 (0.60-7.5)

0.247

3 (≥ 909 pg/mL)

6.9 (3.0-16)

<0.0001

3.2 (1.3-8.1)

0.012

3.3 (1.2-9.1)

0.023

2.5 (0.59-9.0)

0.167