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Figure 3 | Respiratory Research

Figure 3

From: Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling

Figure 3

Evaluation of chronic hypoxia- and Ova-induced increases in percent of medial thickness (%MT) in pulmonary vessels. (A) Paraffin-embedded lung sections from normoxic (28 days, 20.8% O2), hypoxic (28 days, 10.0% O2), saline-challenged, and Ova-challenged mice were rehydrated and stained with Movat’s pentachrome stain. Scale bar: 25 μm. Intra-alveolar (B) and peribronchial (C) %MT in mice exposed to normoxia, hypoxia, saline challenge, and Ova challenge. Data are shown as means ± SEM. The number of vessels counted is indicated within each bar. n ≥ 4 mice for each group. ***P<0.001 versus control.

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