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Table 3 Univariate associations between (A) log-transformed AWT 3.5 and (B) FEV 1 % predicted, and clinical characteristics

From: Low-dose CT measurements of airway dimensions and emphysema associated with airflow limitation in heavy smokers: a cross sectional study

Dependent variable

A. Log-AWT3.5

B. FEV1,% predicted

Beta

p-value

Beta

p-value

Log-AWT3.5

  

−31.21

<0.001

FEV1,% predicted

−0.010

<0.001

  

FEV1, liter

−0.233

<0.001

23.56

<0.001

FEV1/FVC,%

−0.015

<0.001

1.441

<0.001

FVC,% predicted

−0.009

<0.001

0.971

<0.001

Emphysema; Perc15

0.003

<0.001

0.204

<0.001

Emphysema; Log-%LAA −950 HU

−0.041

0.023

−5.872

<0.001

Lung volume on CT, Liter

−0.055

<0.001

−0.257

0.691

Pack-years

0.003

0.003

−0.153

0.004

Smoking (former/current)

0.059

0.065

−3.257

0.071

Age, years

−0.002

0.458

−0.289

0.092

Height, cm

−0.002

0.444

−0.121

0.425

Cough

0.156

<0.001

−9.234

<0.001

CMH

0.114

0.001

−8.171

<0.001

Dyspnea

0.158

<0.001

−11.99

<0.001

Wheezing

0.202

<0.001

−13.26

<0.001

  1. Definition of abbreviations: Log-AWT3.5 = logtransformed airway wall thickness at 3.5 mm diameter; CMH =chronic mucus hypersecretion; Log-%LAA −950 HU = logtransformed percentage of low attenuation areas < −950HU.
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Respiratory Research

ISSN: 1465-993X

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