Table 1 Baseline characteristics of the two study groups
Variable | Healthy | PAH | p-value |
|---|---|---|---|
N = 41 | N = 28 | ||
Age (years) | 34 ±2 | 45 ±2 | <0.01 |
Gender (M/F) | 17/24 | 6/22 | 0.09 |
Smoking history (never/current/ex smoker) | 40/0/1 | 24/1/3 | 0.1 |
Height (cm) | 169 ±1 | 167 ±3 | 0.3 |
Weight (kg) | 79 ±3 | 89 ±7 | 0.2 |
O2 Saturation (% of Hgb) | 98 ±0.2 | 96 ±0.4 | <0.01 |
FENO (ppb) | 19 ±2 | 18 ±2 | 0.7 |
FVC (%) | 98 ±2 | 91 ±3 | 0.2 |
FEV1 (%) | 93 ±2 | 80 ±4 | <0.01 |
FEV1/FVC | 81 ±1 | 75 ±1 | <0.01 |
TLC (%) | 85 ±2 | 82 ±2 | 0.4 |
VA (L) | 4.9 ±0.2 | 4.3 ±0.2 | 0.1 |
DLCO (ml/min/mmHg) | 24 ±1 | 17 ±1 | <0.01 |
DLNO (ml/min/mmHg) | 94 ±4 | 66 ±5 | <0.01 |
Dm (ml/min/mmHg) | 48 ±2 | 33 ±2 | <0.01 |
Vc (ml) | 78 ±4 | 63 ±5 | <0.01 |
Dm/Vc (1/min/mmHg) | 0.6 ±0.02 | 0.6 ±0.04 | 0.8 |
Hgb (g/dl) | 13.3 ±0.3 | 13.5 ±0.4 | 0.9 |