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Table 1 Characteristics of the study population on admission based on Aspergillus spp. isolation

From: Importance of Aspergillus spp. isolation in Acute exacerbations of severe COPD: prevalence, factors and follow-up: the FUNGI-COPD study

 

All patients (n = 240)

No Aspergillusspp. isolation (n = 120)#

Aspergillusspp. isolation (n = 24)#

p-value†

Age, years

74.4 ± 8.8

74.2 ± 10.1

73.1 ± 8.2

0.569

Gender, males

217 (90.4)

103 (85.8)

23 (95.8)

0.246

 Past-smoker

175 (72.6)

87(72.5)

18 (75.0)

0.608

 Current smoker

65 (27.4)

33 (27.5)

6 (25.0)

0.779

FEV1% predicted

2.6 (1-3)

47.3 ± 12.9

45.4 ± 14.7

0.196

FVC% predicted

44.0 ± 14.6

71.9 ± 14.4

68.8 ± 16.4

0.094

Charlson index

69.6 ± 19.6

2.1 (1.3-3.4)

2.7 (1.6-3.9)

0.060

 GOLD stage II

12 (5,8)

8 (6.6)

-

-

 GOLD stage III

92 (38,3)

46 (38.3)

8 (33.3)

0.436

 GOLD stage IV

136 (56,1)

66 (55.5)

16 (66.6)

0.062

COPD exacerbation in the previous year

    

 ≤ 2 exacerbations

82 (53.2)

65 (63.7)

7 (38.8)

0.150

 >2 exacerbations

72 (46.7)

37 (36.3)

11 (61.1)

0.050

Admission for COPD in the previous year

2.6 ± 1.9

2.1 ± 0.8

2.4 ± 1.2

0.079

Long Term Oxygen Therapy

72 (30.0)

36 (29.1)

9 (37.5)

0.067

Cardiovascular disease1

131 (54.6)

61 (50.8)

12 (50.0)

0.475

Arterial hypertension2

112 (46.7)

52 (43.3)

19 (79.2)

0.002

Diabetes mellitus

65 (27.1)

31 (25.8)

9 (37.5)

0.206

Chronic renal disease

34 (14.2)

15 (12.5)

6 (25.0)

0.052

Inhaled corticosteroids

170 (70.8)

85 (70.8)

18 (75.0)

0.763

 <500 mcg daily

106 (62.3)

54 (43.5)

12 (66.6)

0.096

 >500 mcg daily

64 (37.6)

31 (36.5)

6 (33.3)

0.267

Oral corticosteroids

80 (33.3)

39 (32.5)

9 (37.5)

0.284

  1. Data are presented as means ± SD, medians (Interquartile range) or absolute numbers (%), as appropriate. 1Patients with cardiovascular disease other than arterial hypertension; 2Patients with arterial hypertension without any other cardiovascular condition. #Data calculated from the total number of respiratory samples. † p-value refers only to the comparison between non-aspergillus and Aspergillus isolated populations.