Figure 1

The effect of DEP on IL-8 mRNA expression (A) and IL-8 protein release (B) by PBECs exposed to DEP in SFM for 18 h and 24 h respectively. Samples were compared with PBECs cultured in SFM alone. Statistical analysis was carried out using Kruskal Wallis followed by Wilcoxon signed rank test; * p < 0.01 ** p < 0.005 (n = 10). (C) a typical western blot obtained after analysis of activation of the MAPK pathway in PBEC samples exposed to 10, 50 or 200 μg/ml DEP for the times indicated. Data are representative of 4 individual experiments.