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Table 2 Demographics, lung function and markers of systemic and local inflammation In COPD patients divided into current smokers and ex-smokers

From: Lung density on high resolution computer tomography (HRCT) reflects degree of inflammation in smokers

Variables

COPD (current smokers)

COPD (ex-smokers)

N (male/female)

28 (15/13)

12 (5/7)

Age

58.9 ± 5.1

59.8 ± 5.9

Body mass index (kg/m2)

24.1 ± 3.8

27.7 ± 4.0$

Height (Centimetres)

172 ± 1.4

170 ± 2.5

Smoking (pack years)

41.6 ± 10.4

29.1 ± 8.9$$$

Cigarette per day (last 6 months)

16.4 ± 6.4

N/A

Time since smoking cessation years (range)

N/A

(2–16)

FEV1 (% predicted)

79.4 ± 10.8

78.1 ± 14.0

FEV1/FVC

0.61 ± 5.9

0.61 ± 7.8

DLco (% predicted)

66.3 ± 12.1

67.6 ± 15.3

TLC (% predicted)

107.6 ± 16.5

109.6 ± 10.4

RV (% predicted)

137.6 ± 36.9

138.8 ± 25.9

Chronic bronchitis (% of individuals)

25

17

Dyspnoea score (CRQ)

5.9 ± 0.91

6.1 ± 0.72

White blood cell counts (109/L )

8.0 ± 1.9

7.0 ± 1.9

Serum -high sensitive-CRP (g/L)

3.2 ± 3.0

2.7 ± 1.9

Serum -orosomucoid (g/L)

0.86 ± 0.18

0.80 ± 0.12

Serum -haptoglobin (g/L)

1.5 ± 0.45

1.1 ± 0.36$$

Serum -immunoglobulin G (g/L)

9.4 ± 1.7

10.3 ± 2.7

BAL cell concentration (106/L)

492.5 ± 255.3

118.6 ± 69.1$$$

BAL macrophages (106/L)

470.9 ± 250.0

101.2 ± 64.0$$$

BAL lymphocytes (106/L)

13.1 ± 9.0

14.4 ± 8.4

BAL neutrophils (106/L)

4.7 ± 4.1

2.7 ± 2.1

BAL eosinophils (106/L)

3.5 ± 1.9

0.23 ± 0. 13

BAL recovery (%)

43.7 ± 14.8

50.4 ± 12.2

  1. Values are expressed as mean and SD unless otherwise stated.
  2. COPD = chronic obstructive pulmonary diseases; N/A = not applicable; kg = kilogram; m = meter; FEV1 = forced expiratory volume in 1 s; FVC = forced vital capacity; TLC = total lung capacity; RV = residual volume; DLco = carbon monoxide diffusing capacity; BAL = bronchoalveolar lavage; CRQ = chronic respiratory questionnaire; g = gram; L = liter.
  3. $p ≤ 0.05, $$p ≤ 0.01, $$$p ≤ 0.001.