Variables | COPD (current smokers) | COPD (ex-smokers) |
---|---|---|
N (male/female) | 28 (15/13) | 12 (5/7) |
Age | 58.9 ± 5.1 | 59.8 ± 5.9 |
Body mass index (kg/m2) | 24.1 ± 3.8 | 27.7 ± 4.0$ |
Height (Centimetres) | 172 ± 1.4 | 170 ± 2.5 |
Smoking (pack years) | 41.6 ± 10.4 | 29.1 ± 8.9$$$ |
Cigarette per day (last 6 months) | 16.4 ± 6.4 | N/A |
Time since smoking cessation years (range) | N/A | (2–16) |
FEV1 (% predicted) | 79.4 ± 10.8 | 78.1 ± 14.0 |
FEV1/FVC | 0.61 ± 5.9 | 0.61 ± 7.8 |
DLco (% predicted) | 66.3 ± 12.1 | 67.6 ± 15.3 |
TLC (% predicted) | 107.6 ± 16.5 | 109.6 ± 10.4 |
RV (% predicted) | 137.6 ± 36.9 | 138.8 ± 25.9 |
Chronic bronchitis (% of individuals) | 25 | 17 |
Dyspnoea score (CRQ) | 5.9 ± 0.91 | 6.1 ± 0.72 |
White blood cell counts (109/L ) | 8.0 ± 1.9 | 7.0 ± 1.9 |
Serum -high sensitive-CRP (g/L) | 3.2 ± 3.0 | 2.7 ± 1.9 |
Serum -orosomucoid (g/L) | 0.86 ± 0.18 | 0.80 ± 0.12 |
Serum -haptoglobin (g/L) | 1.5 ± 0.45 | 1.1 ± 0.36$$ |
Serum -immunoglobulin G (g/L) | 9.4 ± 1.7 | 10.3 ± 2.7 |
BAL cell concentration (106/L) | 492.5 ± 255.3 | 118.6 ± 69.1$$$ |
BAL macrophages (106/L) | 470.9 ± 250.0 | 101.2 ± 64.0$$$ |
BAL lymphocytes (106/L) | 13.1 ± 9.0 | 14.4 ± 8.4 |
BAL neutrophils (106/L) | 4.7 ± 4.1 | 2.7 ± 2.1 |
BAL eosinophils (106/L) | 3.5 ± 1.9 | 0.23 ± 0. 13 |
BAL recovery (%) | 43.7 ± 14.8 | 50.4 ± 12.2 |