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Table 3 The association of α-tocopherol (α-T) and γ-tocopherol (γ-T) with lung spirometry (year 0 of the CARDIA study)

From: The vitamin E isoforms α-tocopherol and γ-tocopherol have opposite associations with spirometric parameters: the CARDIA study

 

Lung spirometry

BLACKSa

WHITESa

ALL PARTICIPANTSb

N

βc

SE

95% confidence interval

P value

N

β

SE

95% confidence interval

P value

N

β

SE

95% confidence interval

P value

α-T

 

2289

    

2237

    

4526

    
 

FEV1

 

27.6

17.3

-6.3 to 61.6

0.11 #

 

5.5

13.7

-21.4 to 32.4

0.69

 

11.1

10.8

-10.1 to 32.3

0.30

 

FVC

 

40.4

19.7

1.9 to 78.9

0.04*

 

33.4

16.0

2.1 to 64.7

0.04*

 

31.3

12.5

6.8 to 55.8

0.01*

 

FEV1/FVC

 

-0.1

0.3

-0.6 to 0.4

0.78

 

-0.4

0.2

-0.8 to -0.0

0.03*

 

-0.3

0.2

-0.6 to 0.0

0.07 #

γ-T

 

2289

    

2237

    

4526

    
 

FEV1

 

-80.0

37.7

-154.0 to -6.0

0.03*

 

-78.0

47.1

-170.3 to 14.3

0.10 #

 

-73.7

29.5

-131.6 to -15.8

0.01*

 

FVC

 

-106.7

42.8

-190.7 to -22.7

0.01*

 

-107.8

54.8

-215.3 to -0.4

0.05*

 

-97.0

34.1

-163.9 to -30.0

0.005*

 

FEV1/FVC

 

0.3

0.5

-0.8 to 1.4

0.59

 

0.2

0.7

-1.1 to 1.5

0.74

 

0.2

0.4

-0.6 to 1.1

0.58

  1. (Linear regression analysis at year 0 of the CARDIA study).
  2. aAdjustments: center, age, age2, height, height2, sex, BMI, smoking status and ever asthma.
  3. bAdjustments: center, age, age2, height, height2, sex, BMI, smoking status and ever asthma, race.
  4. cβ is the difference in mL of FEV1, mL of FVC or % FEV1/FVC per 10 μM tocopherol.
  5. *and boldface, significant; #and boldface, trend.