The vitamin E isoforms α-tocopherol and γ-tocopherol have opposite associations with spirometric parameters: the CARDIA study

Table 5 Association of α-T with lung spirometry (within quartiles of γ-tocopherol) at year 0 of CARDIA

Quartiles of γ-T	N	Difference in FEV₁per 10 μM α-T	P value	Difference in FVC per 10 μM α-T	P value	Difference in FEV₁/FVC (%) per 10 μM α-T	P value
(μM)	N	β	P value	β	P value	β	P value
A	BLACKS
0.00-3.59	375	73.8	0.03*	62.3	0.11 ^#	0.6	0.20
3.60-4.69	432	-55.7	0.29	1.0	0.99	-1.3	0.05*
4.70-5.99	442	60.7	0.24	37.8	0.52	0.7	0.33
6.00-68.35	547	25.2	0.49	43.8	0.31	-0.3	0.55
B	WHITES
0.00-3.59	538	-13.1	0.53	19.6	0.44	-0.6	0.04*
3.60-4.69	451	27.3	0.44	-18.1	0.65	-0.2	0.64
4.70-5.99	463	10.2	0.79	22.1	0.64	-0.1	0.80
6.00-68.35	358	37.0	0.34	84.4	0.05*	-0.7	0.18
C	ALL PARTICIPANTS
0.00-3.59	913	11.8	0.51	29.9	0.16	-21.7	0.39
3.60-4.69	883	-33.8	0.24	-12.8	0.70	-0.5	0.20
4.70-5.99	905	24.9	0.42	17.9	0.63	0.3	0.51
6.00-68.35	905	20.7	0.43	50.7	0.10 ^#	-0.5	0.16

Nonasthmatics, Year 0 of CARDIA (Adjustments: center, age, age², height, height², sex, BMI, smoking status).
*and boldface, significant; ^#and boldface, trend.

ISSN: 1465-993X