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Figure 4 | Respiratory Research

Figure 4

From: The effects of salbutamol on epithelial ion channels depend on the etiology of acute respiratory distress syndrome but not the route of administration

Figure 4

Real-time polymerase chain reaction analysis of biological markers associated with inflammation [interleukin (IL)-6, macrophage inflammatory protein (MIP)-2, and tumor necrosis factor (TNF)-α], apoptosis [pro-caspase-3, BH3 interacting-domain death agonist (Bid), and Bcl-2-associated X protein (Bax)], and damage inflicted on alveolar type I epithelial cells [receptor for advanced glycation end-products (RAGE)] and endothelium [vascular cell adhesion molecule (VCAM)-1]. All values are expressed as mean and standard deviation. Differences between groups (SALB vs. CTRL; SALB-iv vs. SALB-it) were tested separately for ARDSp and ARDSexp using one-way ANOVA followed by Bonferroni correction. Statistical significance was accepted at α = 0.05. * = p < 0.05 vs. CTRL; NI = non-injured control; CTRL = control; SALB = salbutamol; i.t. = intratracheally; i.v. = intravenously; ARDSp = pulmonary acute respiratory distress syndrome; ARDSexp = extrapulmonary acute respiratory distress syndrome.

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