Table 1 Multiple breath washout parameters
From: Lung clearance index in adults with non-cystic fibrosis bronchiectasis
Method of calculation | Mechanism of ventilation heterogeneity | |
|---|---|---|
LCI | Analysis of basic washout curve | Summary measure of overall ventilation heterogeneity |
LCIvent | Two-compartment model | Specific ventilation inequality: convection-dependent |
LCIds | Two-compartment model | Dead space contribution: diffusion-convection-dependent |
Scond | Phase III slope analysis | Convection-dependent |
Sacin | Phase III slope analysis | Diffusion-convection-dependent |
Scond* | Phase III slope analysis (modified) | Convection-dependent |
Sacin* | Phase III slope analysis (modified) | Diffusion-convection-dependent |