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Table 3 Physiological parameters in patients with and without chronic bacterial colonisation

From: Lung clearance index in adults with non-cystic fibrosis bronchiectasis

 

Non-cystic fibrosis bronchiectasis

Cystic fibrosis

No chronic colonisation

Chronic colonisation

No chronic PsA colonisation

Chronic PsA colonisation

(n = 26)

(n = 17)

(n = 25)

(n = 15)

FEV1 (% pred.)

86.1 (5.3)

75.6 (4.9)

69.7 (4.5)

59.6 (4.5)

FVC (% pred.)

101.7 (4.6)

87.5 (4.1)#

86.9 (3.6)

80.6 (5.5)

FEV1/FVC (%)

68.6 (2.4)

68.1 (2.4)

67.1 (2.5)

63.9 (2.5)

TLC (% pred.)

95.3 (3.1)

93.9 (4.0)

-

-

LCI

10.02 (0.36)

9.95 (0.57)

12.29 (0.72)

14.44 (0.85)

LCIvent

1.42 (0.03)

1.41 (0.05)

1.59 (0.05)

1.75 (0.05)

LCIds

1.27 (0.02)

1.26 (0.03)

1.34 (0.03)

1.49 (0.04)##

Scond (L‒1)

0.058 (0.010)

0.072 (0.010)

0.122 (0.010)

0.132 (0.018)

Sacin (L‒1)

0.429 (0.053)

0.288 (0.038)

0.438 (0.070)

0.611 (0.093)

Scond* (L‒1)

0.102 (0.014)

0.115 (0.016)

0.284 (0.034)

0.294 (0.051)

Sacin* (L‒1)

0.412 (0.053)

0.268 (0.041)

0.376 (0.068)

0.553 (0.092)

  1. PsA = Pseudomonas aeruginosa; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; TLC = total lung capacity; LCI = lung clearance index; LCIvent = specific ventilation inequality component of lung clearance index; LCIds = dead space component of lung clearance index. Data expressed as mean (standard error). Colonised and non-colonised groups within each disease cohort compared using Student’s T test. Significant differences between groups denoted #(p < 0.05) or ##(p < 0.01).