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Figure 7 | Respiratory Research

Figure 7

From: Macrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthma

Figure 7

Macrophage activation state determines the response to subsequent rhinovirus infection. Upon airway injury, individuals with a type 2-predominant immune response experience eosinophilic airway inflammation which is heightened by RV infection. Alternatively, individuals with a type 1/IL-17-predominant response (analogous to IL-4R KO mice) demonstrate neutrophilic inflammation which is exacerbated by RV infection.

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