From: Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels
Variables | GOLD 0 | GOLD 4 | p value |
---|---|---|---|
 | (n = 9) | (n = 11) |  |
Age, years | 65.1 ± 7.4 | 55.5 ± 1.9 | 0.09 (n.s.) |
Male/Female gender | 5/3 | 4/6 | - |
Smoking, pack-year | 22.5 ± 12.1 | 58 ± 10.8 | 0.02* |
Stop years | 32.8 ± 8.9 | 7.2 ± 7.7 | 3.4 × 10−6** |
FEV1, % predicted | 103.4 ± 7.3 | 18.1 ± 1.2 | 3.47 × 10−10** |
FVC, % predicted | 100.8 ± 8.1 | 48.5 ± 3.7 | 6 × 10−10** |
FEV1/FVC | 75 ± 1.9 | 32 ± 3.9 | 4 × 10−8** |