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Figure 2 | Respiratory Research

Figure 2

From: Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2

Figure 2

Aspergillusantigen-induced lung inflammation appears similar in wild-type,Mcp-1-/-andCcr2-/-mice. H&E stained lung sections from PBS- or Aspergillus antigen-treated wild-type, Mcp-1-/- and Ccr2-/- mice. Representative normal airway from wild-type control mice (A) (similar findings from Mcp-1-/- and Ccr2-/- control mice are not shown). Representative lung sections from Aspergillus antigen-treated wild-type (B), Mcp-1-/- (C) and Ccr2-/- mice (D) demonstrate intense peribronchiolar and perivascular inflammation. Aspergillus antigen exposure and sample collection are described in methods. Magnification: 20× objective.

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Respiratory Research

ISSN: 1465-993X

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