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Figure 4 | Respiratory Research

Figure 4

From: Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2

Figure 4

Aspergillusantigen induced goblet cell hyperplasia in wild-type,Mcp-1-/-andCcr2-/-mice. Representative PAS-stained lung sections from PBS-treated wild-type mice (A) showed minimal PAS-positive staining (similar findings from Mcp-1-/- and Ccr2-/- control mice are not shown). Aspergillus antigen-treated wild-type (B), Mcp-1-/- (C) and Ccr2-/- mice (D) showed magenta staining in epithelial cells, which represents mucus. Aspergillus antigen exposure and sample collection are described in methods. Magnification, 40× objective.

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Respiratory Research

ISSN: 1465-993X

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