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Figure 7 | Respiratory Research

Figure 7

From: Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2

Figure 7

Increased airway subepithelial collagen deposition after treatment withAspergillusantigen. Representative lung sections from PBS-treated mice show minimal trichrome staining around small airways (A) (similar findings from Mcp-1-/- and Ccr2-/- control mice are not shown). Increased trichrome staining is noted around small airways in Aspergillus antigen-treated wild-type (B), Mcp-1-/- (C) and Ccr2-/- (D) mice. Blue staining around airways represents collagen. Aspergillus antigen exposure and sample collection are described in methods. Magnification, 20× objective.

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