Table 4 Expression of nAChR in Airway Fibroblasts as determined by RT-PCR
NLFB | α1 | α3 | α5 | α6 | α7 | α9 | β1 | β2 | β3 | β4 | δ | ε |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Never smoker | 5/5 (100%) | 2/5 (40%) | 5/5 (100%) | 5/5 (100%) | 5/5 (100%) | 5/5 (100%) | 5/5 (100%) | 5/5 (100%) | 2/5 (40%) | 2/5 (40%) | 5/5 (100%) | 5/5 (100%) |
Active smoker | 10/11 (91%) | 3/11 (27%) | 11/11 (100%) | 8/11 (73%) | 10/11 (91%) | 11/11 (100%) | 11/11 (100%) | 8/11 (73%) | 4/11 (36%) | 2/11 (18%) | 10/11 (91%) | 10/11 (91%) |
Ex-smoker | 9/9 (100%) | 0/9 (0%) | 8/9 (89%) | 5/9 (56%) | 5/9 (44%) | 8/9 (89%) | 6/9 (67%) | 6/9 (67%) | 2/9 (22%) | 3/9 (33%) | 9/9 (100%) | 8/9 (89%) |
Total | 24/25 (96%) | 5/25 (20%) | 24/25 (96%) | 18/25 (72%) | 20/25 (80%) | 24/25 (96%) | 22/25 (88%) | 19/25 (76%) | 8/25 (32%) | 7/25 (28%) | 24/25 (96%) | 23/25 (92%) |