Figure 6

Concentrations of aerosolised MCh required to induce a doubling of the saline response in the airways (A), or a 50% increase in the response of the lung parenchyma (B, C) of weanling mice. Significantly lower concentrations of MCh were required to induce responses at 7 and 10 d post infection in Raw (A), 7 d in G (B) and 5 and 7 d in H (C). The response at 10 d post infection was more consistent than in adult mice, however responsiveness in general was much more variable in weanlings.