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Table 1 Baseline airway and tissue mechanics in adult and weanling mice. Values: mean (SE).

From: Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice

Age

Treatment

Weight (g)

Raw hPa.s.ml-1

G hPa.ml-1

H hPa.ml-1

Adult

Control 5 d

19.3 (0.4)

0.33 (0.02)

5.1 (0.2)

37.3 (1.3)

 

Control 21 d

17.9 (0.6)

0.33 (0.02)

5.4 (0.5)

36.5 (2.3)

 

RSV 5 d

17.1 (0.2)

0.38 (0.03)

5.2 (0.2)

40.9 (1.8)

 

RSV 7 d

18.2 (0.3)

0.35 (0.03)

5.9 (0.3)

44.3 (2.4)

 

RSV 10 d

16.7 (0.3)

0.39 (0.03)

5.2 (0.3)

41.5 (2.1)

 

RSV 21 d

18.7 (0.4)

0.43 (0.02)

4.8 (0.3)

40.3 (2.5)

Weanling

Control 5 d

13.9 (0.6)

0.51 (0.04)

7.0 (0.4)

61.6 (2.6)

 

Control 21 d

16.7 (0.6)

0.48 (0.03)

6.5 (0.8)

57.7 (2.9)

 

RSV 5 d

13.9 (0.5)

0.53 (0.08)

7.6 (0.4)

69.6 (5.7)

 

RSV 7 d

15.1 (0.3)

0.52 (0.03)

7.8 (0.5)

64.0 (3.1)

 

RSV 10 d

15.5 (0.5)

0.52 (0.05)

8.5 (0.7)

65.6 (6.7)

 

RSV 21 d

16.3 (0.5)

0.39 (0.02)

6.3 (0.4)

45.1 (3.5)*

  1. * p < 0.05 vs. d5 control, not significant vs. d21 control