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Figure 9 | Respiratory Research

Figure 9

From: Biphasic effect of extracellular ATP on human and rat airways is due to multiple P2 purinoceptor activation

Figure 9

Effect of indomethacin and H-89 on ATP-induced contraction in rat isolated airway rings. A: Fmax to 10-3 M ATP in rat airway rings in the presence of 10 μM indomethacin. Horizontal bars are Fmax in control conditions. B: TR10 in rat airway rings stimulated by 10-3 M ATP in the presence of 10 μM indomethacin (n = 5 to 8) C: TR10 in rat airway rings stimulated by 10-3 M ATP in the presence of H-89 (n = 8). Trachea: black column; left (LEPB) and right EPB (REPB): hatched columns; left IPB: cross-hatched column. Vertical bars are TR10 in control conditions. Error bars are SEM. *P < 0.05.

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