α1-AT/SPA ratio | α1-AT | Z α1-AT | ||||||
---|---|---|---|---|---|---|---|---|
Reaction condition | Kass, (M-1sec-1) | decrease in K ass, n-fold | Reaction condition | Kass, (M-1sec-1) | decrease in K ass, n-fold | |||
α1-AT nM | SP-A nM | Z α1-AT nM | SP-A nM | |||||
7.5 | 0 | 3.40 ± 0.0079 × 107 | 0 | 7.5 | 0 | 9.80 ± 0.0032 × 106 | 0 | |
50 | 7.5 | 0.15 | 1.84 ± 0.0577 × 107 | 1.8 | 7.5 | 0.15 | 5.20 ± 0.0314 × 106 | 1.9 |
5 | 7.5 | 1.5 | 1.70 ± 0.0623 × 107 | 2 | 7.5 | 1.5 | 4.70 ± 0.0268 × 106 | 2.1 |
1 | 7.5 | 7.5 | 5.20 ± 0.0483 × 106 | 6.5 | 7.5 | 7.5 | 4.30 ± 0.0240 × 106 | 2.3 |
0.5 | 7.5 | 15 | 4.30 ± 0.0513 × 106 | 7.9 | 7.5 | 15 | 3.80 ± 0.0221 × 106 | 2.6 |